| ClCr range ml/min |
SCr range |
Prophylactic Dose |
|---|---|---|
| > 60 | < {{Cr60}} | 900mg PO od |
| 40 - 59 | {{Cr60}} - {{Cr40}} | 450mg PO od |
| 25 - 39 | {{Cr40}} - {{Cr25}} | 450mg PO alt days |
| 10 - 24 | {{Cr25}} - {{Cr10}} | 450mg PO twice weekly |
| < 10 | > {{Cr10}} | not recommended |
Calculations based on {{wt_type}}
Ideal body weight {{ibw | number:1}}kg
This dosing tool can used to audit renal dosing of valganciclovir used for CMV prophylaxis after renal transplantation. It gives creatinine ranges corresponding to the creatinine clearance thresholds, based on a patient with a specified age and weight, derived from the Cockcroft-Gault formula for estimation of creatinine clearance.
The serum creatinine ranges can be expressed in μmol/l or mg/dl as preferred, and it is possible to toggle between the units just by changing the unit selector in the form.
By default, the calculations use the patient's actual body weight, but by specifying a height it is also possible to calculate the ranges by ideal body weight, based on BMI of 23 for female patients and 21.5 for males.